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Jae Kwagh Selected Research

BMS-986094

1/2017In Vitro Metabolite Formation in Human Hepatocytes and Cardiomyocytes and Metabolism and Tissue Distribution in Monkeys of the 2'-C-Methylguanosine Prodrug BMS-986094 : Potential Role in Clinical Cardiovascular Toxicity.
10/2016Effects of BMS-986094, a Guanosine Nucleotide Analogue, on Mitochondrial DNA Synthesis and Function.

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Jae Kwagh Research Topics

Disease

2Mason-Type Diabetes
06/2006 - 04/2005
1Virus Diseases (Viral Diseases)
01/2017
1Chronic Hepatitis C
01/2017
1Hepatocellular Carcinoma (Hepatoma)
10/2016
16 familial Hyperinsulinemic hypoglycemia
06/2006
1Hyperglycemia
06/2006
1Type 2 Maturity-Onset Diabetes of the Young
06/2006
1Hyperinsulinism (Hyperinsulinemia)
04/2006
1Hyperammonemia
04/2006
1Hypoglycemia (Reactive Hypoglycemia)
04/2004

Drug/Important Bio-Agent (IBA)

2BMS-986094IBA
01/2017 - 10/2016
2Proteins (Proteins, Gene)FDA Link
06/2006 - 04/2004
2GlucokinaseIBA
06/2006 - 04/2005
2Adenosine Triphosphate (ATP)IBA
04/2006 - 04/2004
1ProdrugsIBA
01/2017
1Mitochondrial DNA (mtDNA)IBA
10/2016
1EnzymesIBA
06/2006
1Glutamate DehydrogenaseIBA
06/2006
1Leucine (L-Leucine)FDA Link
06/2006
1Guanosine Triphosphate (GTP)IBA
04/2006
1PotassiumIBA
04/2004